Safety and immunogenicity of SARS-CoV-2 recombinant protein vaccine formulations in healthy adults: interim results of a randomised, placebo-controlled, phase 1–2, dose-ranging study - The Lancet Infectious Diseases
A controlled human infection model of Streptococcus pyogenes pharyngitis (CHIVAS-M75): an observational, dose-finding study - The Lancet Microbe
Embaixada da Bélgica em Portugal / Embassy of Belgium in Portugal | Facebook
Frontiers | Exploration of the Optimal Desmopressin Treatment in Children With Monosymptomatic Nocturnal Enuresis: Evidence From a Chinese Cohort | Pediatrics
Safety and immunogenicity of a chimpanzee adenovirus-vectored Ebola vaccine in healthy adults: a randomised, double-blind, placebo-controlled, dose- finding, phase 1/2a study - The Lancet Infectious Diseases
Study design. Oral typhoid vaccine Ty21a dose schedule (4 doses at... | Download Scientific Diagram
Contemporary strategies to improve clinical trial design for critical care research: insights from the First Critical Care Clinical Trialists Workshop | SpringerLink
Single-arm, open-label, dose-escalation phase I study to evaluate the safety of a herbal medicine SH003 in patients with solid cancer: a study protocol | BMJ Open
Safety and immunogenicity of a high-dose quadrivalent influenza vaccine administered concomitantly with a third dose of the mRNA-1273 SARS-CoV-2 vaccine in adults aged ≥65 years: a phase 2, randomised, open-label study -
A first in man, dose-finding study of the mTORC1/mTORC2 inhibitor OSI-027 in patients with advanced solid malignancies | British Journal of Cancer
The role of organizational characteristics on the outcome of COVID-19 patients admitted to the ICU in Belgium - The Lancet Regional Health – Europe
The essential role of Interactive Response Technology (IRT) in Clinical Trial Supply - Sharp Packaging Services
Efficacy and Safety of Mirikizumab in a Randomized Phase 2 Study of Patients With Ulcerative Colitis - Gastroenterology
A phase I dose-escalation and pharmacokinetic study of a micellar nanoparticle with entrapped docetaxel (CPC634) in patients with advanced solid tumours - ScienceDirect
Adding flexibility to clinical trial designs: an example-based guide to the practical use of adaptive designs | BMC Medicine | Full Text
A phase 3 randomized placebo-controlled trial to assess the efficacy and safety of ipragliflozin as an add-on therapy to metformin in Russian patients with inadequately controlled type 2 diabetes mellitus - Diabetes
Dynamic changes in paediatric invasive pneumococcal disease after sequential switches of conjugate vaccine in Belgium: a national retrospective observational study - The Lancet Infectious Diseases
Statistical controversies in clinical research: requiem for the 3 + 3 design for phase I trials - Annals of Oncology
Interim Results of a Phase 1–2a Trial of Ad26.COV2.S Covid-19 Vaccine | NEJM
A phase 1 dose escalation study of the oncolytic adenovirus enadenotucirev, administered intravenously to patients with epithelial solid tumors (EVOLVE) | Journal for ImmunoTherapy of Cancer | Full Text
Designing phase II trials in cancer: a systematic review and guidance | British Journal of Cancer
LIVE BLOG: R&D response to COVID-19 pandemic | Science|Business
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Phase I Clinical Trials — Celine Halioua
How to design a dose-finding study on combined agents: Choice of design and development of R functions
Dose-Finding Designs for Early-Phase Cancer Clinical Trials | SpringerLink
Design considerations for phase I/II dose finding clinical trials in Immuno-oncology and cell therapy - ScienceDirect
